A cancer cell line is a population of cancer cells, grown from a patient’s tumor, that keeps living and dividing in the lab. It acts as a stand-in for that tumor: researchers use cell lines to understand how a cancer grows and to test whether a drug works before it is given to people. Ours are grown directly from tumor samples donated by today’s patients.
Our cell lines are living cancer cells, not tissue on a slide or data in a file. They keep growing, so they can be frozen, revived, shared, and tested again and again. Because they are alive, a drug can be applied to them directly to see how the tumor responds.
Drug developers can test new therapies on cell lines that match the patients they are designing for: specific subtypes, mutations, ancestries, and prior treatments, including tumors that have become resistant. They learn earlier which drugs work, and for whom, before investing years in a clinical trial.
We’ve developed proprietary methods for establishing our cell lines and monitoring them over time, so they stay faithful to the patient. We sequence the fresh tumor tissue when we collect it, then sequence the cell line once it’s established, and again at later points before any drug testing. Comparing each cell line to the tumor it came from confirms it still represents that patient.
Growing living cell lines from patient tumors is slow and hard, and many samples don’t grow at all. Most existing collections were built by individual labs for their own studies, so they stayed small. Biopharma companies don’t have the capacity to keep collecting new samples and growing cell lines from them.
Now that has changed. Deep characterization works at scale, and our proprietary technology makes growing and evaluating these cell lines repeatable.
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